Did They Steal Her Discovery? The Untold Scandal of DNA!

While James Watson and Francis Crick are famously recognized for describing the double helix structure of DNA in 1953, it's a common misconception that they "invented" DNA. The molecule itself was first identified by Friedrich Miescher in the 1860s. However, the crucial understanding of DNA's spiral shape and precise dimensions came from the groundbreaking work of British chemist Rosalind Franklin. Her meticulous X-ray crystallography experiments, particularly the famous "Photo 51," provided indispensable evidence directly pointing to the helical nature of DNA.

Unfortunately, Franklin's vital contributions were largely uncredited during her lifetime, as her data was shared with Watson and Crick without her direct consent. While Watson, Crick, and Maurice Wilkins received the Nobel Prize in 1962 for the DNA structure, Franklin, who had passed away, was not included. Today, there's growing recognition of Rosalind Franklin's pivotal role and the significant impact of her scientific rigor on one of the 20th century's most important discoveries.

Welcome to the 120th edition of ResusNation!

Did You Register For ResusX:2025 Yet?

If you're serious about resuscitation, then we'll see you at ResusX:2025 in Philadelphia. With over 30 world-class speakers, live-demoes, debates, fun and prizes, this will be the BIGGEST event we've ever run. Tickets are running out and right now you can save $400 off registration by using the code RESUSX400 at checkout.  

Watch the full video here and leave a comment.

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We just launced the ResusX:Workshops series, four incredible hands on workshops that will help you take your ressucitation skills to the next level. Whether you attend these on their own, or part of ResusX, you will level up your skills. Choose from on of the following:

• Total Ariway Workshop
• DysRhythmia Day with Amal Mattu
• Resus:Ready Procedure Workshop
• The Vent Workshop

Full schedules are available below and spots are very limited, so don't wait until the last minute to register!

GET MY TICKET FOR THE WORKSHOP 

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18% Reduction in Mortality: How Ultrasound is Changing Septic Shock Treatment

Sepsis can quickly lead to septic shock and increased mortality. Despite aggressive care, assessing a patient's heart function and fluid status in real-time can be challenging. This new review and meta-analysis, involving nearly 4,000 patients, investigated whether adding a quick, bedside ultrasound of the heart – called point-of-care echocardiography (POC echo) – could improve outcomes for these very sick patients. The exciting news? Integrating POC echo into standard care was associated with a significant decrease in patient deaths. 

The study found that using POC echo in septic shock management led to an 18% lower risk of in-hospital and 28-day mortality. It also meant that doctors were more likely to start better inotropic support, and patients achieved faster lactate clearance.While POC echo showed benefits, the study did note that different protocols were used across the included studies, which can make direct comparisons difficult. Despite this, the findings suggest a powerful new role for bedside ultrasound in guiding critical treatment decisions, potentially leading to better and more personalized care for patients fighting septic shock. 

Here's my Takeaways:

• Finding: Point-of-care echocardiography guided management in septic shock patient was associated with an 18% lower in-hospital and 28-day mortality.

• Practice Impact: Integrating POC echocardiography can lead to more frequent initiation of inotropic support and shorter time to achieve lactate clearance.

• Population: The study included both adult and pediatric patients in septic shock within the ICU setting.

• Limitation: Differences in POC echocardiography protocols and the inclusion of both experimental and observational studies limit direct comparison and standardization.

Want to learn more? Read the full study "The association between integrating echocardiography use in the management of septic shock patients and outcomes in the intensive care unit: a systematic review and meta-analysis" by Keith Killu et al. in Journal of Ultrasound (2025)

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Do you want even more resus content anytime you want? For less than a cup of coffee, you can get even more content from @CriticalCareNow. Digital teaching sessions, free video lectures, grand rounds, and so much more can be your today. Come watch on replay all the content that @CriticalCareNow does live. 

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