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ResusNation #116

May 12, 2025
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Can Tiny Robots Smaller Than a Hair Save Your Brain?


The frontier of modern medicine is constantly expanding, and one of the most revolutionary areas involves exploring the potential of medical nanorobotics. These are microscopic robots, designed with incredible precision to operate within the intricate environment of the human body. A particularly promising application lies in the treatment of brain aneurysms. Imagine a future where, instead of complex surgical procedures, a fleet of these tiny robots could be introduced into the bloodstream, guided with pinpoint accuracy using external technology, directly to the site of a vulnerable aneurysm. There, they could be tasked with delivering a targeted therapy, perhaps releasing a substance to encourage clotting and reinforce the weakened vessel wall, thus preventing a potentially life-threatening rupture.

Nanorobotics represents a paradigm shift in how we approach delicate medical interventions. The ability to deploy therapeutic agents and perform repairs at a nanoscale offers unprecedented precision, potentially minimizing the risks and recovery time associated with more invasive techniques. While still a field of active research and development, the progress in medical nanorobotics for conditions like brain aneurysms underscores the exciting trajectory of modern medicine – moving towards highly localized, intelligent treatments that could transform patient care and offer new hope for previously intractable conditions.


Welcome to the 116th edition of ResusNation!



Start To Appreciate "The "Collateral Beauty" of Emergency Medicine

It's so true. In the midst of the chaos and often heartbreaking situations we face in emergency medicine, it's vital to remember the profound opportunity we have to make a real difference. I've seen it countless times – the incredible resilience of patients and their families, the unwavering support from colleagues, and even small acts of kindness that shine through the darkest moments. It's these glimmers of hope and our ability to offer comfort and aid during their most vulnerable times that, for me, underscore the inherent beauty in what we do.

This ability to step in, to apply our skills and knowledge to alleviate suffering, and to offer a sense of control in a situation that feels utterly uncontrollable for the patient – that's a privilege. It's not about ignoring the gravity of the situation, but rather recognizing the profound impact we can have. Even in the face of loss and despair, our presence and our actions can bring a measure of solace and make a tangible difference in someone's life.

Watch the full video here and leave a comment.

Don't forget to like and follow my IG, TikTok, YT, Facebook or Linkedin accounts.


Early-Bird Tickets Are Almost Sold-Out !

ResusX:2025 is the most anticipated resuscitation conference of 2025 is now open for early-bird registration! Come to historic Philadelphia and spend three-days watching the Rockstars of Resuscitation in action. You'll see short format, high-energy talks, interviews, procedure demoes, and debates. ResusX is not simply a conference, but a resuscitative experience where you are part of the show and spend lots of time after the conference hanging out with the faculty. 

Registration will not only give you full-access to the conference but also a swag bag filled with a t-shirt, mug, stickers, and a ton more. Food and snack is on us and you'll also be elibigble to earn up to 20.0 CME or CEU credit. We got your trip covered with on-site parking and an available hotel block.

We will also be offering a selection of post-conference workshops on October 2 & 3 including:

  • Amal Mattu's ECG workshop
  • UltraRounds: the resuscitative ultrasound workshop
  • ResusReady: a procedural workshop for resuscitationists
  • The Total Airway Workshop
  • The Resuscitationist Guide To The Vent

Today is your opportunity to take your resuscitation skills to the next level and save big with our early-bird discounts. Come to ResusX, learn the skills and save more lives. Click on the link below to register for your early-bird tickets now.

 REGISTER NOW

 


Talking Shift: The Cognitive Pause

Talking Shift: The Cognitive Pause

 

Drawing on a real-life case of refractory hypotension initially treated as sepsis, Dr. Anand Swaminathan and I discussion highlights the cognitive traps that can keep clinicians locked onto a single diagnosis. We talk about a practical checklist to run through during this crucial pause, exploring often-overlooked causes of shock and poor response to treatment. 

Throughout this episode Swami emphasizes that patients can, and often do, have multiple simultaneous pathologies (Hick's dictum), challenging the often-taught idea of a single unifying diagnosis (Occam's Razor). By building the cognitive pause into your resuscitation practice, you can enhance your ability to identify missed diagnoses, pivot your management effectively, and ultimately improve patient outcomes.

Check out this video of Anand Swaminathan from ResusX:ReVolved now!

 Watch the Video Now!


 

A Survival of 1.5% In Asystole?

Out-of-hospital cardiac arrest (OHCA) is a global health crisis, claiming millions of lives annually. When the heart stops, it can do so with a shockable rhythm or a non-shockable rhythm like asystole. While much focus has been on shockable rhythms, a new study highlights the urgent need to address asystole, which is increasingly common. This research, a systematic review and meta-analysis, examined global data on EMS-treated patients with initial asystole. The sobering finding: overall survival to hospital discharge or 30 days was just 1.5%.  

This is a stagering statistic for anyone that manages patients in arrest. The current study, which included data from 35 countries and over 540,000 patients, reveals that survival rates for asystolic OHCA remain extremely low, and neurological outcomes are often poor. Researchers emphasize the importance of prevention strategies and better adherence to termination of resuscitation (TOR) guidelines. While the findings are limited by heterogeneity across multiple studies, it strongly suggests a need to rethink current approaches to improve patient outcomes.  

Here's my Takeaways:

  • Finding: Pooled survival to hospital discharge or 30 days was only 1.5%.
  • Practice Impact: Emphasizes need for prevention and adherence to termination of resuscitation (TOR) guidelines.
  • Population: 540,054 EMS-treated patients across 35 countries.
  • Limitation: High clinical and statistical heterogeneity across studies.

Effect of hydrocortisone on mortality in patients with severe ...

Listen to this episode from ResusX:Podcast on Spotify. In this episode, we're diving into the latest research on hydrocortisone use in cr...

open.spotify.com

Want to learn more? Read the full study: "Incidence and outcomes of out-of-hospital cardiac arrest from initial asystole: a systematic review and meta-analysis" by Dwivedi et al. in Resuscitation.  


Life is short. Don’t waste it formatting manuscripts (AKA why we built Resub)

Formatting a manuscript to meet needlessly specific journal requirements is thankless, repetitive, and — let’s be honest —waste of time. 

We built Resub to automate this entire process:

  • Upload your manuscript.

  • Select your target journal.

  • Resub will reformat headings, references, spacing, figures, and even checklists.

  • You download a clean, journal-ready version — in minutes.

What makes Resub different is that it doesn’t just generate "generic templates." It reads your actual text, restructures it, and checks it against real journal guidelines.
No plagiarism, no messing with your writing flow — just automation of the formatting steps that used to take hours.

As a CritCareNow reader, you get $100 off your subscription with the code CritCareNow.

➡️ Watch the demo here: See Resub in Action


Watch the May's Videos Now!

  

If you're an All-Access Member, you're in for some great content this month. We have FIVE videos hand-picked by our staff that are high-yield and our most highly watched. We're featuring

  • Ducanto on "Bougie Down"
  • Crager on "Reimagining Shock"
  • Rezaie vs Swaminathan on "The Great CPR Debate"
  • Gutierrez on "Peripheral Vasopressors"
  • Rezaie on "TEG/ROTEM"

Each month we bring you fresh new content from the best of the best in resuscitation. If you're an All-Access member, go watch these videos NOW! If you're not, then sign up here.


Are you a member of ResusNation? For less than a cup of coffee, you can get even more content from CriticalCareNow. Digital teaching sessions, podcasts, free video lectures, grand rounds, and so much more can be your today. Come watch on replay all the content that CriticalCareNow does live. Check out the membership options below and decide the right one for you.


Do you want even more resus content anytime you want? For less than a cup of coffee, you can get even more content from @CriticalCareNow. Digital teaching sessions, free video lectures, grand rounds, and so much more can be your today. Come watch on replay all the content that @CriticalCareNow does live. 

Check out the membership options below and decide the right one for you.


 Get Access To The ResusNation Today!


 

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